I have encountered the same issue; have just submitted the following bug report to Opera so hopefully will get addressed in the next few days....
The 1Password Extension has been working normally until (probably) Friday 11th September. It appears that a recent Opera update has ‘broken’ the 1Password functionality so when you try opening it from the extensions top bar an empty frame opens but not the actual pop-up 1Password window (see 1st .png attachment below).
I have tried the usual steps to resolve without success:
Followed the guidance on the 1Password support pages Tried various standard permutations of closing Opera and 1Password desktop individually and collectively; restarted the apps; rebooted the PC, etc. Uninstalled the 1Password extension Reinstalled (https://chromewebstore.google.com/detail/1password-–-password-mana/aeblfdkhhhdcdjpifhhbdiojplfjncoa ) Edited the Registry to inset a new Key HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Opera and inserted a new DWORD: NativeHostsExecutablesLaunchDirectly set to 1. This has had no effect.I note that there are other mentions of this issue on the Opera Forum
I have also tried installing the Google Chrome browser as a cross-check and the 1Password Extension works perfectly and as expected with that.
I’d greatly appreciate if you can check out what seems to have happened with the recent Opera update and resolve so I can get this very useful functionality back working again
Many thanks,
Best regards,
Kevin
PS.
Have just spotted that this is under the 'Opera for Mac' Category - should have been under Opera for Windows but imaging is likely the same issue affecting both editions. Request the Forum Team move or duplicate to the correct Category.