Just thought I would share this, because it's really annoying. I was able to find a post from a dev on the 1Pass forums.
Thank you for reaching out. Opera isn't a supported browser for 1Password which means that integration between the 1Password desktop app and the browser extension won't work. An issue in previous versions of 1Password may have allowed you to use app integration with Opera but this issue has since been fixed. You may still be able to use 1Password in Opera but you'll need to unlock the browser extension using your account password.
On the Mac, we recently released a custom trusted browsers feature which allows you to add any browser with a valid code signature to 1Password for Mac. The team is hoping to bring this feature to Windows in the future but it's not available currently.
For the moment, if you'd like to have 1Password in your browser share a lock state with the desktop app so that it can use features like Windows Hello, you can switch to one of our supported browsers such as Chrome, Firefox, Brave, or Microsoft Edge.
Let me know if you have any questions.
This is the thread on their forums: https://1password.community/discussion/146235/opera-must-keep-entering-master-password
So, 1Pass working in Opera (desktop and extension connected) was a bug? And they fixed the bug before adding the trusted browser feature? As much as I love 1Pass (I've been using it for 10 years), I have lost a lot of respect for them. They're not some small company anymore and it doesn't take a lot of resources to keep all chromium browsers supported. They could have at least not fix the bug until their trusted browser feature is ready.
Pure insanity.