It's what I did before with Brave, but I have definitely switched to Opera as my default browser.
I have used Opera settings quite extensively to determine who is or isn't allowed to use cookies, and a few specific ones automatically to delete on exit, I used my Brave settings as a pattern to follow. It's basic Chrome stuff.
But in general my set up is permissive for primary cookies and not to allow third party cookies.
But every so often I use CCleaner to delete cookies. But with the exception of what I term "business" cookies, which I have listed in CCleaner.
This worked for me just fine with Brave, and with the addition of a few VPN exceptions seems to be going well with Opera so far.
Note that I do not rely on CCleaner for all clean up tasks.
But as long as I'm changing things around a lot right now, I'm interested in hearing about alternative ways to do this, in particular if there is an Opera compatible extension for very selective cookie culling.
Thanks.