There's a good chance it's antivirus software that's causing it. Bitdefender, Kaspersky and Eset for example. You might have to temporarily uninstall them to and not just disable them to test if they're interfering with Opera. You might want to reinstall Opera after uninstalling them too.
Subcategories
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Future releases
Let's talk about latest and greatest in Opera world: experimental builds, beta and developer versions
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Suggestions and feature requests
Is there some feature you would love see added to Opera browser on computer? Let us know!
Opera for computers