I have returned to uBlock Origin from the built-in ad blocker again until Opera’s ad blocker matures to the point we no longer need extensions. uBlock Origin should be more than plenty for ad blocking. It is possibly the most lightweight extension there is currently. The additional CPU cycles by ad block extensions do not matter for modern PCs.
Combining multiple ad blockers is generally not a good idea if that is what you meant by ‘lettering the built handle some generic stuff’.