How does Chrome display pages?
If poorly like Opera, then I would suggest some video driver incompatibility - Opera and Chrome share same rendering engine.
If correctly, then it is likely problem with Opera settings or so; try Opera portable version - does that work better?
The bookmarks manager in Opera and the bookmarks in "my account" in Opera sync (of course when syncing is on) do not sync. I showed a picture of that a few posts ago. I also asked/said "How do I restore items (bookmarks, folders with bookmarks in it) that are only visible in my "opera account" (https://sync.opera.com/web/) to my opera browser ?"
I will try to elaborate on this later, but in the meantime do not close this thread. Thank you.
In some cases, anti-malware on one's own computer can interfere with the proxy nature of Opera's VPN.
However, if you live in a number of countries where there is national censorship, your ability to connect with a VPN may be interfered with or blocked by your ISP or the national Internet backbone to prevent circumvention of the censorship. This is particularly true for certain nations in the Middle East and the Orient, but can also occur in a few other nations where national politics or geopolitical tensions lead to attempting restriction of citizen access to web traffic to/from beyond the national borders. Some forum threads that relate to what may happen are:
In some cases, your ISP (Internet Service Provider) may be blocking VPN usage (or its distinctive header protocols), either intentionally or accidentally. If there's no 'political' risks to the user, it may be useful to inquire about the problem with your ISP.
Sometimes, if censorship is involved, one can try using a stand-alone VPN service in hopes that it won't be blocked, though eventually that can happen with any VPN if the national authorities are persistent.
edited to add: If you live in Russia, you may be encountering something related to the subject of this article, which is expected to occur before 1 April 2019: https://www.bbc.com/news/technology-47198426
Yes, indeed it does, thank you! It appeared that I have to hold the wheel being pressed for the very long time (a couple of secs perhaps) to make a click successfuly. Guess I need another mouse, thought of Logitech better