Finally, "Auto-sync data" option in phone settings causes Opera running in background. Unchecking that, issue's gone.

Phone Settings > Accounts => tap on the three dots (upper right) and uncheck Auto-sync data:
0_1544239499429_Accounts.png 0_1544239517015_Accounts1.png

Of course, Opera Startup option should be set to "Continue where I left off".

Opera Settings > Startup => "Continue where I left off"
0_1544240538372_Startup.png 0_1544240552736_Startup1.png

Setting above two options, Opera stays closed after "Force Stop" till next time I'll use it.

@sgunhouse Topic solved. Thanks for your help!