If you uninstall Opera, does explorer still freeze? If not, then yes, it's totally possible that Opera could be interfering in some way. But, it doesn't seem too likely.

@Mozza7 said in Crash issues Windows 10:

I recently reinstalled win10 entirely.

If you haven't gotten too far in setting everything back up yet, consider reinstalling again just to rule out issues with the Windows 10 installation.