--disable-gpu

Thanks... it works!!

Did you try a reinstall?

Yes I have, and it didnt resolve the problem...

I'm encountering a similar issue, see this post for more info:
https://forums.opera.com/post/124894
Some users suggest enabling/disabling hardware acceleration, if you can get past the blank screen anyways. Please update if you find a solution that works for you.

I have read the thread, but it seemed that there are no way to turn off HW Acceleration outside Opera... I even cant open the setting....

After the latest Windows update occuring at 13th July 2017, my PC restarted and after that I cant run Opera at all... All I see is a white Window and the mouse cursor is always loading.... Is there any solution for this?