Welcome to Opera's forum @Lankidave!

Is there any VPN (orange) icon in the address bar?
If so, click > Switch off > Refresh, test

··· IF NOT ···

Try to navigate from OMenu > New private window
If so:

Do you have any extension?
Try disabling them, test. (Proxy extensions could block the navigation if they stop working)

Ctrl + Shift + Del and clean # 4 and 7, refresh or restart, test.

Still problems?
Ctrl + Shift + Del and add to the clean # 3, refresh or restart, test.

··· STILL? ···

Create a new profile (clean profile), Steps on forum's "FAQ..."
You'll need to set up Opera again.

For Bookmarks, OHelp > Find solution > Back Up
Or if works, use OSync.