Welcome to Opera's forum @Lankidave!
Is there any VPN (orange) icon in the address bar?
If so, click > Switch off > Refresh, test
··· IF NOT ···
Try to navigate from OMenu > New private window
Do you have any extension?
Try disabling them, test. (Proxy extensions could block the navigation if they stop working)
Ctrl + Shift + Del and clean # 4 and 7, refresh or restart, test.
Ctrl + Shift + Del and add to the clean # 3, refresh or restart, test.
··· STILL? ···
Create a new profile (clean profile), Steps on forum's "FAQ..."
You'll need to set up Opera again.
For Bookmarks, OHelp > Find solution > Back Up
Or if works, use OSync.