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I am having the same issues with Opera and the flash version 23.0.0.162 did system restore takes me back to previous flash 22.0.0.209. all seems fine on the 22 version. Make sure you don't have it set to auto update to the latest version though, otherwise it will re-install 23.0.0.162.
Thank you Tom Marshall, the information you gave me to fix my PPAPI Flash worked and i have no problems now !!! You RAWK !!!
How do i find out and where do i look to see if its auto up-dated ?
Well i spoke to soon, it didnt work after all 
After i refreshed the browser and went into a game, it did fine until i went or tried to go into another game Same thing still happening
Well i spoke to soon, it didnt work after all After i refreshed the browser and went into a game, it did fine until i went or tried to go into another game Same thing still happening
Well i spoke to soon, it didnt work after all After i refreshed the browser and went into a game, it did fine until i went or tried to go into another game Same thing still happening
Thank you Leocg for taking the time and trying to help me out on this ! All i did was Google, "Why doesnt my PPAPI Plug in work for me in Opera, and i found the solution !! 
Thank you again xxx
Yes, i am having the same problem as tuzzyteal is ........... And there seems to be no way to get ahold of Opera to let them know of such problem This sux !!!
http://prnt.sc/ci5lul , http://prnt.sc/ci5m29 , http://prnt.sc/ci5ma5 ..... All 3 of these have in () that it is (out-of-process) ??? Does that mean anything ???
I have tried several games but each one of them says the plug-in can not be loaded. I am up to date on my Adobe Flash Player. I have used 2 other browsers and both of those load facebook games just fine. Why am i have this problem on game playing with "just" Opera ???