I recently installed the latest stable release of Opera (v46) on my PC (Windows 10) and I noticed that the font aliasing issue from years ago is still around.
The most obvious place I spotted these font issues are right here on the Opera Discussion boards.
Here are two screenshots to show the difference between fonts in Opera and Chrome on the same PC:
Opera:
http://i738.photobucket.com/albums/xx27/xietoun/Screenshots/Opera Fonts_zpsyjga8vms.png
Chrome:
http://i738.photobucket.com/albums/xx27/xietoun/Screenshots/Chrome Fonts_zpsdj1ffzcu.png
As in the screenshots, the fonts in Opera look crooked and aliased. It's most obvious in characters s, p, and o, which show jagged edges.
I have tried several proposed solutions, including using the experimental flags, to no avail.
I really want to use Opera as my main browser but reading on it is unbearable because of these issues.