Ok, it is fixed now.
I re-read your posts and went and looked at my extensions. For some reason I missed disabling "YouTube Center". I disable this extension and all is well.
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I tried disabling all the extensions I have (e.g. Adblock, video pinner) but still the page renders wrong. It's like the top part of the page (where the links to the videos are) gets partially covered by the top part of the web page and makes those parts unusable. I can't include a snippet here.
I am running Opera Next (20.0.1387.59) on Windows 7 64-bit (WoW64).
I go to the YouTube page and whether I am looking at my subscribed videos in grid or list mode the top row's link is not usable as it won't show as a link. (No clickable link - although the coloring of the link suggests it should be a link)
The next row or video in the grid/list is fine.