@ss9227 I tested --disable-features=DIPS, and it increases the time until permissions are lost, or adds some one-time longer delay, until permissions are lost again, but it does not "solve" the issue. When I added this to my Opera startup link, permissions remained stable for maybe a week, before the issue reappeared. Afterwards, it happened again much sooner, though I did not test yet whether every 1-2 hour like before.
Allowing 3rd party cookies is even worse than disabling DIPS, as the latter is meant to make disabling 3rd party cookies more reliable. I won't test this, as I do not want to make it too easy for advertisement networks to track me across websites.
But that this has an effect as well for you, shows that the bug is somehow tied into the 3rd party cookie/privacy protection stuff. But while it has an effect, it does not seem to be the exact trigger for the lost permissions.


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. Maybe Opera can bring it back? 