@hucker @mixchild I think I found a workaround.
1/ Remove the extension which is corrupted (among Opera)
2/ Explorer > Right-click on %USERPROFILE%\AppData\Roaming\Opera Software\Opera Stable\ and uncheck the Read-only flag, click Apply.
3/ Close Opera and check if any process is still running before restart it
I have been able to remove Chrome extension enabler \o/