You can request such configuration via business enquiries form: http://www.operasoftware.com/company/contact/form
In Extreme mode our servers download all resources for your page, render the page and then send result to the client (for example in Africa). As long as there is a reasonable link between your web server and Opera Mini servers, the distance is not that important. Most typically problems with long page loading are caused by some JavaScripts and ad frameworks.