I went ahead and got the update from opera.com. Tried out media background play with YouTube and audio not only kept playing when the tab was in the background, but when Opera itself was in the background.
Best posts made by dharden
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RE: Opera for Android 91Opera for Android
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RE: YouTube doesn't work anymore.Opera GX
@andrew84 That could be. It could explain why the problem I had literally came on overnight, and maybe even why it was so weirdly specific. (Videos would play unless I was trying to play them in a youtube.com tab that saw me as signed in.) It could also explain why they are working again, as of now. (I'm 6 hours behind CEST, if that matters.)
Anyway, "try to update the adblock lists" and/or "wait for an update to the adblock lists" may be something to put on the list of things to try when something like this happens.