@leocg I tried to copy these 2 folders C:\Users\xxxxxx\AppData\Local\Opera Software
C:\Users\xxxxxx\AppData\Roaming\Opera Software from other PCs (overwrite, copy after a fresh install, delete existing folders then copy, etc.), but the issue is still there.
Would you please specify which files or folders should I pay more attentions? Thx.

@leocg fresh install and clean profile work well, But which mean I need to reset up dozens of extensions, layout, etc.

Opera suddenly can't remember login when check 'remember login' on one of my PCs. It maybe occurred when I updated to 53 or 54. I have five PCs with Opera, other four are working well with 'remember login'. And on this dysfunctional one, Opera can remember a few sites 'remember login', but not for all. These sites can't be 'remembered login' on the dysfunctional one, can be remembered on other four. What happen to that one?

how to disable hardware acceleration? even setting page is loading...

new installed windows 10 with latest updates

install latest stable opera 32

BLUE SCREEN!!!