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As announced for my phone, on which Opera only worked if Secure Folder was disabled, I proceeded to test the solution proposed by miyukiwork/efolch:
I therefore confirm the effectiveness of the solution.
Thanks to all for the contributions.
@efolch
Very interesting.
I confirm that I also found "Mobile Services Manager" on my phone. Only later will I be able to do some tests by reinstalling the Secure Folder to see if Opera still works even with the active one.
I agree that I'm hoping for a fix from Opera so I don't have to keep a system app disabled (even if it doesn't seem to have any use for the user).
Considering that for someone the problem was solved by installing a different Launcher, the problem could be linked more precisely to One UI 5.0 than to Android 13. A problem that does not occur with One UI 4.1.
@miyukiwork
I don't have "DT ignite" or similar apps on my phone (as far as I can tell). 
Opera only works if I don't activate the Secure Folder, so there must still be some link (with Android 12 Opera and the Secure Folder worked together without problems).
@salimanilaslan
As far as we see at Opera they are just now getting the right feedback on the cause of the problem.
In reality it is a particular case and not too widespread (Samsung phone, Android 13, Secure Folder active, ...), even if it is spreading.
I was lucky to discover the cause because on the day it stopped working, the only change was the activation of the Secure Folder. A few weeks later I tried to activate again but Opera crashed again until I deactivated Secure Folder again. I searched the web with little success until I found this forum, where there was a description of the same problem but no one had yet associated it with the Secure Folder.
From now Opera should be able to replicate the problem and find a solution (assuming that the problem should not be solved by Samsung).
@guidoglx
Have you done exactly what is in the link posted?
On my S21 FE the app was removed, and Opera came back...
-Samsung S21 FE
-Android 13
-Opera and Opera Beta crash as soon I try to open the app
-Opera Mini works perfectly.
In my experience Opera stops to work creating a Secure Folder (https://www.samsung.com/uk/support/mobile-devices/what-is-the-secure-folder-and-how-do-i-use-it/).
After a complete uninstal of Secure Folder (see link above), Opera works again without issues.
In tha past "Android 12 / One UI" configuration both Opera and Secure Folder works
@guidoglx
Try to read here:
https://www.samsung.com/uk/support/mobile-devices/what-is-the-secure-folder-and-how-do-i-use-it/
section
How do I remove the Secure Folder?
Sorry for the late reply, but I couldn't find the correct English name for the function.
@riccardomineo
Same problem for me:
Samsung S21 FE
Android 13
Opera and Opera Beta crash as soon I try to open the app
Opera Mini works perfectly.
Solved Removing The Samsung Personal Area.
Once uninstalled the personal area the Opera App back to normal behavior and works.
I suppose there is something that doesn't work between Opera and Personal Samsung Personal Area in Android 13 UI 5.0
