Same happens here. Have disabled hw accel, no difference. I have my bookmarks toolbar visible and clicking the ">>" button to see more doesn't cause Opera to crash. Hovering the mouse over the Bookmarks menu item (which is supposed to trigger opening a second pane with my bookmarks in it) crashes Opera in just a couple seconds (barely enough time to notice the orb appear, signaling that it probably should be trying to load them).
This is unlikely related to the user's profile and more likely a bug (to be addressed soon, hopefully).