Here is, what helped me:
- Close running Opera
- Rename folder with profile: "C:\users%username%\AppData\Roaming\Opera Software\Opera Stable" to ".\Opera Stable old" (The "healthy" profile should be "Opera Stable 2, 3,..." depends in what phase of crash you are now - basicly it is the largest folder"
- Install latest version of Opera from offline installer
- Close again the automatic-opened failed try
- Rename folder with profile: "C:\users%username%\AppData\Roaming\Opera Software\Opera Stable" to ".\Opera Stable bad"
- Create in folder "C:\users%username%\AppData\Roaming\Opera Software" new own folder ".\Opera Stable"
- Take ownership of folder "Opera Stable old" EVEN if you are owner already
- Copy everything from folder "Opera Stable old" into your new folder "Opera Stable"
- Opera should start normally.