I am new to Opera, and to this forum.
I came here exactly because I was having this problem on Google Chrome.
Also with VPN and streaming video.
In my case it was soccer games streaming through a non-Twitch site. In Chrome, VPN is added through an extension, and when I disable this extension, things seem to go fine. The Out of Memory problem also seems to happen when VPN is active, for all sites with streaming video.
I also am using Windows 10, with a NVidia GeForce card and an old HP workstation (but with 8 gig memory). I have not yet experienced the problem in Opera, but I am new. . . (posted because this was similar to the problem that brought me to Opera today).