I'm having the same issue. Windows 8.1. My display's resolution is 3200x1800, but I've set it to resolution to 2048 x 1152 with 125% zoom to make things readable. I think somehow the problem has to do with the display zoom? Here's a picture that shows the issue: both Opera and Paint.net are at 100% zoom, but they show at different sizes.
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RE: Everything is bigger after updating to Opera 24Opera for Windows