@rakeshsingh Resolved with "--force-device-scale-factor=1.25"
I map Super+O in XFCE to launch /usr/bin/opera-gx --force-device-scale-factor=1.25

Not recommended, but I also changed the shortcut.

bat /usr/share/applications/opera-gx.desktop ─────┬───────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────── │ File: /usr/share/applications/opera-gx.desktop ─────┼───────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────── 1 │ [Desktop Entry] 2 │ Version=1.0 3 │ Name=Opera GX 4 │ GenericName=Web browser 5 │ Comment=Fast and secure web browser 6 │ TryExec=opera-gx 7 │ Exec=opera-gx --force-device-scale-factor=1.25 %U 8 │ Terminal=false 9 │ Icon=opera-gx 10 │ Type=Application 11 │ Categories=Network;WebBrowser; 12 │ MimeType=text/html;text/xml;application/xhtml_xml;x-scheme-handler/http;x-scheme-handler/https;x-scheme-handler/ftp;application/x-opera-download; 13 │ Actions=new-window;new-private-window; 14 │ StartupWMClass=Opera GX 15 │ 16 │ [Desktop Action new-window] 17 │ Name=New Window 18 │ Exec=opera-gx --force-device-scale-factor=1.25 --new-window 19 │ TargetEnvironment=Unity 20 │ 21 │ [Desktop Action new-private-window] 22 │ Name=New Private Window 23 │ Exec=opera-gx --force-device-scale-factor=1.25 --incognito 24 │ TargetEnvironment=Unity