I'm experiencing the same problem too. I'm using the latest version 39.0.2256.71 on windows 10 and it generally happens if I have a few javascript-heavy tabs open (facebook, gmail, etc) so it looks like it might be a memory leak of some kind?
I have already turned off mouse gestures, and the problems persists. Not had this problem with Chrome which I recently switched from, but I'm seriously considering switching back to chrome because I am losing work.