With my (old) laptop lenovo R61:
Chipset : Mobile 965 Express
GPU : intel GM965
Graphic Driver (latest available) : 18.104.22.1680 WHQL
Windows 7 x64
No screen flickering with Opera 44, everything works well. But I can use Opera 45.xxx because of screen flickering.
A workaround is to start opera 45 with --disable-gpu-compositing, but the CPU load = +50%