@naheed said in Open PDF, not saving:

It is not Opera's issue.
You need to download/save the pdf file and then choose a default program to open the saved pdf file.
It will always open the saved pdf file in the chosen program.

It is absolutely 'Opera's Issue'. There's a menu item that provides 'save with changes' in the upper right context menu that does not work. It saves a file that isn't edited. That's an Opera Issue.