Well, I've tried everything that was suggested here and nothing has worked. So I just never close Opera. Hardly a good fix but a little less frustrating at any rate.
Thanks for all your help

Uninstalled it, then redownloaded Opera and got my extensions running. Closed it then restarted it. Same problem. Extensions are gone.
SO frustrating!

New profile? Don't know how to do that. Can't find anything about it in help either

Still can't get it to work right. Maybe I should go back to Mozilla sigh

Make sure your user account has permission to write to the profile folder / settings file.

Not sure how to do that but I know that I am the only "user" that has access to the laptop. Have only one profile.

in ccleaner under pragramms opera uncheck internet history deleting these in any chrome engine browser with ccleaner destroy themes and addons

Nothing is checked in CCleaner till I check it myself. Mainly because I use it often but not always for the same reason.

I'll try a new profile I guess. goes away scratching his head

This only started when Opera updated itself, which I find annoying, as it usually means problems but I'm not complaining. I've used it for many years. Free. If I had paid for it I'd be more than mildly annoyed.

I noticed I have 2 files on my computer for Opera
27.xxx and
28.xxx
I was tempted to delete the 28.xxx folder but I seriously doubt it is going to be that easy, so I left it alone till someone much more tech savvy can help me.

It appears that my settings aren't being saved. My theme is still there, it just doesn't appear. Also when I open Opera up again the feedback bar\question always pops up like it was the first time I opened it.
Shutting down CCleaner's monitoring didn't help.
Any other ideas?
Thanks for your help, much appreciated.

CCleaner V5.03

But bookmarks etc are still there

My theme is gone as well