Hi @captaincolon, you can disable it as follows:

Start the Opera, go to Opera's menu, select "About Opera" (or press Alt, then a), copy the path to the profile, and close the Opera,

Open Windows Explorer (WinKey+E), paste the path into the address bar, find the "Preferences" file, and make its copy (e.g. "Preferences-back" - just in case, if you make a mistake in the syntax, so then you can overwrite the original file with the copy, to revert the changes), and then open the "Preferences" file in your text editor,

At the very top (in the second line), after the first occurrence of the "{" sign, add the code as below:

"Keybindings": { "Basic": { "NavFavorites" : [ "Alt+Home" ] }, "Settings": { "AdvancedEnabled": true } },

after you add the code, it should looks as below:

{ "Keybindings": { "Basic": { "NavFavorites" : ["Alt+Home"] }, "Settings": { "AdvancedEnabled": true } },

Small note: if sections as above already exist, then you should edit them, to be the same as above, and do not add new.

Save the changes, close the file, and launch the Opera 😉