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@venceslau
It seems a problem with the version of Opera browser or with his properties. Try to restart the default values of Opera and see if the problem fix it. If the problem persists try to search more information about this problem on the web. But is very strange the problem 
¡Bravo Opera! 
Dejando a sus usuarios nutrirse de muchas de las extensiones de provecho de Google Chrome, otro motivo más por el que hacerlo tu navegador predeterminado y dejar atrás los demás navegadores del mercado.
I can't use the Mode Picture-in-Picture in Opera, Some pages like Youtube or Vimeo I can use it without problems, but in pages like Amazon Prime Video I can't use this mode. Had anybody any solutions to this problem?
Thanks