I just found this thread via google (on chrome) on my work laptop. I am having this same problem running a win 10 machine.
I have (1) cleared cookies for all time (2) updated opera (3) un-installed and re-installed opera entirely (4) shutdown, re-booted, etc.
Nothing is fixing this issue. It's maddening. And when I go home to my desktop, which is in the same town (across the park) from where I work, I am NOT having this issue at all. Only on my work laptop, which I admittedly keep on my desk at work and do not generally take it out and about.