Opera freezes indefinitely at start

A Former User

Hi guys, I'm having a huge issue and no solution, hope you can help.

Since yesterday, for now apparent reason I can't use Opera anymore. When I launch it, it freezes indefinitely. I can force kill it, it works sometime but sometime a process stay active and can't be killed.
I have no idea what caused this. The browser was opened for a couple of hours and suddenly it just stopped working.

What I attempted so far :

Restart computer
Run as administrator
Uninstall/Reinstall the latest version, and even older versions
Delete the folders from /Local and /Roaming, then uninstall and restart the computer. Install it again, same issue.
Sacrifice a chicken
Cleaned data and registry with CCLeaner
Antivirus check using Adware cleaner
Latest windows update (the issue happened before I updated)

My gear :

Windows 10
Opera latest version (must be 53)
I do not run a tier antivirus software, just Win Defender

Any clue ?

Thanks