I'm using v45 and still having the same problem. I know "doesn't work" isn't a very useful bug report, so here are some more details. When I click the VPN slidebar, it turns orange and says "Connecting..." It stays that way indefinitely, never turning blue. The only way I can seem to get it to work is to close all Opera windows, then restart my computer. When the computer reboots, I have to open the browser and turn on the VPN very quickly. If I wait a few minutes before opening the browser and trying to turn on the VPN, it never connects.
If I sleep or hibernate the computer, I am unable to reconnect the VPN after it wakes up. I have to close everything and reboot again. I tried disabling Windows firewall to ensure it wasn't the problem; no effect.
Windows7 Ultimate, Dell Latitude E6520, 8GB RAM
AVG free version (no firewall), Iobit Malware Fighter, Spybot S&D
Hope this gives you enough info to reproduce. I'm sure some of the other folks above are experiencing this problem (and no doubt others who don't know how to use discussion groups!)
Thank you so much for including a free VPN in your browser. This has gotten me to abandon my other browsers in favor of yours. Now we just need to iron out a few of the inevitable kinks!