For Opera Stable, if you enable both opera://flags/#ffmpeg-demuxer-everywhere and opera://flags/#chromium-ua-compatibility, you might get things to work. For example, if you get through the ads for an episode and the video doesn't play, reload the page (or restart and reload the page) so that the poster for the episode load where you can click to play. Then it might work fine.
For Opera Developer, things should work fine. But, you'll still need opera://flags/#chromium-ua-compatibility.