Following Fitts' Law and the rule of the infinite edges, it is much easier to click on a button if it is all the way at the corner or edge. Since there is effectively infinite area to click on.
All popular browsers do this. It is much more efficient.
The new design is a massive step back in that regard.
In full screen mode, it would be nice if all the tabs and other buttons(like the opera button and workspace buttons on the top left) would be moved all the way to the edges for easy selection.
The way it is now, it is a lot slower to use with a lot more required precision.
The gaps might look nice, to some people, but they make it much less usable.