Hi jimunderscorep,
I am experiencing the same issues. The manipulation suggested does not solve them.
I am running an Nvidia 1070 with proprietary drivers (984.90) on Ubuntu 17.10.
I have noted some graphic stuttering of the desktop when opera is running - and it all ends up crashing when opening a new window (not 100% of the time, but very often)... The mouse still moves, but the UI remains inert. After waiting a few minutes in that state, the mouse becomes extremely laggy.
I hope this helps a bit.