I forgot to mention most important thing. Reinstaling and reconfiguring of
-opera
-fontconfig
-fontconfig-config did not canged a thing.
Once opened in debug mode
opera --enable-logging=stderr --v=1
I noticed some informations about missing cache file
After purging every single cash directory related to opera
rm -rf ~/.cache/opera
rm -rf ~/.config/opera/Default/Sessions
rm -rf ~/.config/opera/Default/Code\ Cache
rm -rf ~/.config/opera/Default/GPUCache
rm -rf ~/.config/opera/Default/Cache
this pice of shoit started working again.