I made it work again!
First of all I uninstalled GHub and deleted all keyboard drivers in device manager (don't know if its necessary but I did)
After that I made I backup of my opera gx settings just in Case something would go messy after my next step.
Now I restarted the PC and wanted to uninstall opera GX but instead of uninstalling I saw the option to reinstall gx. So I did reinstall it with Not Deleting my Data.
I installed GHub again and restarted my PC Again.
When I now went to the operagx lights settings I saw that opera gx was switched off, and when I switched it on again my keyboard went black. (I wouldnt recommend the music visualiser)
So I restarted the PC again started ghub and opera and it worked!
If you ever have to change something on you keyboards light settings first deactivate gxlights inside of opera browser. This will give you controlls of your lights back again and after you finished switch gxlights on again.
Don't unconnect operagx inside of ghub because you will have to uninstall and reinstall all programs again like described before.