Using Windows 10 Pro. Every unnecessary update of Opera seems to screw up Opera. And this was the latest one. Unable to open or do anything else with Opera. But my solution to all things Opera is to use Revo uninstaller to nuke it, supposedly including all it's traces, and then reinstall Opera. None of the above sugestions worked. Nuked Opera, reinstalled, and it worked as a perfect update, even leaving my history and bookmarks intact. How it left my history and bookmarks intact this time, I don't understand, but it did.