@burnout426 Did all that, problem still persists. The problem persists on all brand installations of Opera on computers that have never had Opera installed on them and persists on brand new installs of both Windows 10 and Windows 11. With no sign in and no importing of any data from my desktop. All is done with an administrator account on local accounts, not MS accounts. There's no importing of inherently 'bad' or 'corrupt' data.
If it is indeed a so-called corrupt profile, then the issue lies within Opera's own programming because there is no other explanation for a profile to self corrupt on a brand new Windows install without third party AV, power outage/service interruption, with nothing connecting my desktop profile to a fresh new install using the latest available Windows. Or the fault lies with Microsoft.