@Fildefer @Berry62 here, please give more specifics on your system using systems tab in windows. Show what version and hardware your using. This is most likely a firmware driver issue. I'm running version 122.0.5643.142 on a Dell w11 PC without any issue. My patch level update is 22H3 (KB5001716) KIV that some windows patches break the OS so you may need to control them manually. Click on windows+tab settings+Update_history. You may have to back changes out or perform a fresh install of windows and opera-stable.

This image will help you block popups from annoying adware. 

@adejonghm I had the same issue caused by adware affecting my browser. I did these things to remove it.
On linux-mint I used timeshift to go GOBACK to a safe restore point. I enabled "block-adware" on Opera Advance->settings->

• "Block ads and surf the web faster" -enabled

• Block trackers "manage exceptions-w gmail" -enabled.

• Install a third partner extension "Badger" -enabled.