@simoncrowder Late reply but I found this thread when looking for a solution for Opera.
Same problem with black window on my Lenovo W520 with a Quadro 1000M.
Solution is to set the Opera application to use the integrated graphics using the Nvidia Control Panel.
These are the steps:
Open Nvidia control panel; C:\Program Files\NVIDIA Corporation\Control Panel Client\nvcplui.exe
choose "Manage 3D settings"
then the tab "Program settings"
Add Opera application if it is not in the drop down list
Choose "Integrated graphichs"
That is it!
You can also add more applications in the list that have problems with the Quadro 1000M.