@sgz001 said in Opera 9.21 spontaneously closes.: I tried uninstalling and reinstalling, but it still does it. Did you also delete your profile to start with a new one? If not, the issue could be in the profile folder. You could rename operaprefs.ini (not operaprefs_default.ini) to see if that fixes anything. You could delete autosave.win in the sessions folder. Mail is definitely a possibility.