Ruining this command from Terminal blocks the AutoUpdate. defaults write com.operasoftware.Opera OPDisableAutoUpdate true About why the latest update broke the start up, I don't know. You should try with a clean install or wait for the next update (despite that it's not assuring to fix the problem.) For the clean profile, look at here. Windows 10 (x64) | Anniversary Update Opera Stable · Beta · Developer Opera Test profile | Opera Back up Linux · Mac · Win