Even after rename the original "Opera Software" folder and without copy any older file?
If Opera worked fine before, has been any recent change?
I've been using Opera for months and it's worked perfectly up to now. The only thing I can think of was that I installed Desktop Calendar a few weeks ago. I'll uninstall this and see if it helps.
I don't know if it matters, but I've been having other weird things go on, such as certain games not loading. I don't know if it's related but I thought I'd mention it.
If Opera failed at the very first time, try allowing it on the Antivirus Software or test it disabling it for a while.
I will try this also.