Some weeks ago I tried relocating my Opera installation to a different drive and accessing it through a junction or a symbolic link at the old location pointing to the new location. Everything worked perfectly until I did an update to a new version. This caused havoc. The junction or symbolic link was deleted (!) and replaced by a folder with the same name, but the new folder contained only the data portion of my installation while the program itself remained in the new location but - as the link was detroyed - could not be accessed anymore as before. I never encountered an aggressive behaviour of this kind. Other browsers like Vivaldi comply without problems with the relocation.
Any advice except "don't" ?